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Time course of DNA adduct formation in peripheral blood granulocytes and lymphocytes after drinking alcohol

Alcohol consumption is an established risk factor for cancers of the head and neck, colorectum, liver and female breast. Acetaldehyde, the primary metabolite of ethanol, is suspected to play a major role in alcohol-related carcinogenesis. Acetaldehyde binds to DNA resulting in formation of adducts....

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Autori principali: Balbo, Silvia, Meng, Lei, Bliss, Robin L., Jensen, Joni A., Hatsukami, Dorothy K., Hecht, Stephen S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382307/
https://ncbi.nlm.nih.gov/pubmed/22406526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/mutage/ges008
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