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Kinetics of DNA adduct formation in the oral cavity after drinking alcohol

BACKGROUND: Alcohol consumption is one of the top-10 risks for the worldwide burden of disease and an established cause of head and neck cancer as well as cancer at other sites. Acetaldehyde, the major metabolite of ethanol, reacts with DNA to produce adducts, which are critical in the carcinogenic...

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Detalhes bibliográficos
Main Authors: Balbo, Silvia, Meng, Lei, Bliss, Robin L., Jensen, Joni A., Hatsukami, Dorothy K., Hecht, Stephen S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319307/
https://ncbi.nlm.nih.gov/pubmed/22301829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-11-1175
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