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Immunological cell type characterization and Th1–Th17 cytokine production in a mouse model of Gaucher disease

Gaucher disease is a lysosomal storage disease resulting from insufficient enzyme acid β-glucosidase (glucocerebrosidase, GCase, EC 4.2.1.25) activity and the resultant accumulation of glucosylceramide. Macrophage (Mφ) lineage cells are thought to be the major disease effectors because of their secr...

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Detalhes bibliográficos
Main Authors: Pandey, Manoj Kumar, Rani, Reena, Zhang, Wujuan, Setchell, Kenneth, Grabowski, Gregory A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382074/
https://ncbi.nlm.nih.gov/pubmed/22595426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2012.04.020
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