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Immunological Cells and Functions in Gaucher Disease

The macrophage (MΦ) has been the focus of causality, research, and therapy of Gaucher disease, but recent evidence casts doubt its solitary role in the disease pathogenesis. The excess of glucosylceramide (GC) in such cells accounts for some of the disease manifestations. Evidence of increased expre...

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Detalhes bibliográficos
Main Authors: Pandey, Manoj Kumar, Grabowski, Gregory A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661296/
https://ncbi.nlm.nih.gov/pubmed/23510064
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