Global gene expression profile progression in Gaucher disease mouse models

BACKGROUND: Gaucher disease is caused by defective glucocerebrosidase activity and the consequent accumulation of glucosylceramide. The pathogenic pathways resulting from lipid laden macrophages (Gaucher cells) in visceral organs and their abnormal functions are obscure. RESULTS: To elucidate this p...

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Main Authors: Xu, You-Hai, Jia, Li, Quinn, Brian, Zamzow, Matthew, Stringer, Keith, Aronow, Bruce, Sun, Ying, Zhang, Wujuan, Setchell, Kenneth DR, Grabowski, Gregory A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032697/
https://ncbi.nlm.nih.gov/pubmed/21223590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-20
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