N-(phosphonacetyl)-L-aspartate induces TAp73-dependent apoptosis by modulating multiple Bcl-2 proteins: Potential for cancer therapy

p53 is essential for the cellular responses to DNA damage that help to maintain genomic stability. However, the great majority of human cancers undergo disruption of the p53-network. Identification and characterization of molecular components important in both p53-dependent and -independent apoptosi...

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Detalhes bibliográficos
Main Authors: Amin, A.R.M. Ruhul, Thakur, Vijay S, Gupta, Kalpana, Agarwal, Mukesh K, Wald, David N, Shin, Dong M, Agarwal, Munna L
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382011/
https://ncbi.nlm.nih.gov/pubmed/22430213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.96
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