N-(phosphonacetyl)-L-aspartate induces TAp73-dependent apoptosis by modulating multiple Bcl-2 proteins: Potential for cancer therapy

p53 is essential for the cellular responses to DNA damage that help to maintain genomic stability. However, the great majority of human cancers undergo disruption of the p53-network. Identification and characterization of molecular components important in both p53-dependent and -independent apoptosi...

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Autores principales: Amin, A.R.M. Ruhul, Thakur, Vijay S, Gupta, Kalpana, Agarwal, Mukesh K, Wald, David N, Shin, Dong M, Agarwal, Munna L
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382011/
https://ncbi.nlm.nih.gov/pubmed/22430213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.96
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