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N-(phosphonacetyl)-L-aspartate induces TAp73-dependent apoptosis by modulating multiple Bcl-2 proteins: Potential for cancer therapy

p53 is essential for the cellular responses to DNA damage that help to maintain genomic stability. However, the great majority of human cancers undergo disruption of the p53-network. Identification and characterization of molecular components important in both p53-dependent and -independent apoptosi...

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Bibliografiske detaljer
Main Authors: Amin, A.R.M. Ruhul, Thakur, Vijay S, Gupta, Kalpana, Agarwal, Mukesh K, Wald, David N, Shin, Dong M, Agarwal, Munna L
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382011/
https://ncbi.nlm.nih.gov/pubmed/22430213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.96
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