p53-dependent p21-mediated growth arrest pre-empts and protects HCT116 cells from PUMA-mediated apoptosis induced by EGCG

The tumor suppressor protein p53 plays a key role in regulation of negative cellular growth in response to EGCG. To further explore the role of p53 signaling and elucidate the molecular mechanism, we employed colon cancer HCT116 cell line and its derivatives in which a specific transcriptional targe...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Thakur, Vijay S, Amin, A.R.M. Ruhul, Paul, Rajib K, Gupta, Kalpana, Hastak, Kedar, Agarwal, Mukesh K, Jackson, Mark W, Wald, David N, Mukhtar, Hasan, Agarwal, Munna L
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2010
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914167/
https://ncbi.nlm.nih.gov/pubmed/20444544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2010.04.012
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