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Single-molecule Tracking of Collagenase on Native Type I Collagen Fibrils Reveals Degradation Mechanism
BACKGROUND: Collagen, the most abundant human protein, is the principal component of the extracellular matrix and plays important roles in maintaining tissue and organ integrity. Highly resistant to proteolysis, fibrillar collagen is degraded by specific matrix metalloproteases (MMPs). Degradation o...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3382001/ https://ncbi.nlm.nih.gov/pubmed/22578418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2012.04.012 |
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