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Real-time tracking of single-molecule collagenase on the native collagen and partially-structured collagen-mimic substrates

The dynamic interactions of an individual matrix metalloproteinase-1 were imaged and monitored in the presence of either triple-helical or non-triple-helical, partially-structured collagen-mimic substrates. The enzyme exhibited ten-fold increased catalytic turnover rates with the structurally modifi...

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Detalhes bibliográficos
Publicado no:Chem Commun (Camb)
Main Authors: Froberg, James, Choi, Woo-Sik, Sedigh, Abbas, Anajafi, Tayebeh, Farmakes, Jasmin, Yang, Zhongyu, Mallik, Sanku, Srivastava, D. K., Choi, Yongki
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6145137/
https://ncbi.nlm.nih.gov/pubmed/30091759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8cc04601h
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