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Real-time tracking of single-molecule collagenase on the native collagen and partially-structured collagen-mimic substrates
The dynamic interactions of an individual matrix metalloproteinase-1 were imaged and monitored in the presence of either triple-helical or non-triple-helical, partially-structured collagen-mimic substrates. The enzyme exhibited ten-fold increased catalytic turnover rates with the structurally modifi...
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| Pubblicato in: | Chem Commun (Camb) |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6145137/ https://ncbi.nlm.nih.gov/pubmed/30091759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8cc04601h |
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