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Internal strain drives spontaneous periodic buckling in collagen and regulates remodeling

Fibrillar collagen, an essential structural component of the extracellular matrix, is remarkably resistant to proteolysis, requiring specialized matrix metalloproteinases (MMPs) to initiate its remodeling. In the context of native fibrils, remodeling is poorly understood; MMPs have limited access to...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Dittmore, Andrew, Silver, Jonathan, Sarkar, Susanta K., Marmer, Barry, Goldberg, Gregory I., Neuman, Keir C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968713/
https://ncbi.nlm.nih.gov/pubmed/27402741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1523228113
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