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Accurate extension of multiple sequence alignments using a phylogeny-aware graph algorithm

Motivation: Accurate alignment of large numbers of sequences is demanding and the computational burden is further increased by downstream analyses depending on these alignments. With the abundance of sequence data, an integrative approach of adding new sequences to existing alignments without their...

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Autors principals: Löytynoja, Ari, Vilella, Albert J., Goldman, Nick
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381962/
https://ncbi.nlm.nih.gov/pubmed/22531217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts198
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