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A model of evolution and structure for multiple sequence alignment

We have developed a phylogeny-aware progressive alignment method that recognizes insertions and deletions as distinct evolutionary events and thus avoids systematic errors created by traditional alignment methods. We now extend this method to simultaneously model regional heterogeneity and evolution...

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Detalhes bibliográficos
Main Authors: Löytynoja, Ari, Goldman, Nick
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592536/
https://ncbi.nlm.nih.gov/pubmed/18852103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2008.0170
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