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Accurate extension of multiple sequence alignments using a phylogeny-aware graph algorithm

Motivation: Accurate alignment of large numbers of sequences is demanding and the computational burden is further increased by downstream analyses depending on these alignments. With the abundance of sequence data, an integrative approach of adding new sequences to existing alignments without their...

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Detalles Bibliográficos
Main Authors: Löytynoja, Ari, Vilella, Albert J., Goldman, Nick
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381962/
https://ncbi.nlm.nih.gov/pubmed/22531217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts198
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