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Carboetomidate Inhibits Alpha4/Beta2 Neuronal Nicotinic Acetylcholine Receptors at Concentrations Affecting Animals

BACKGROUND: Carboetomidate is an etomidate derivative that produces hypnosis without inhibiting adrenal corticosteroid synthesis. Like etomidate, carboetomidate modulates γ- aminobutyric acid type A receptors, but its effects on other ion channel targets of general anesthetics are unknown. METHODS:...

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Autori principali: Pierce, David W., Pejo, Ervin, Raines, Douglas E., Forman, Stuart A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381859/
https://ncbi.nlm.nih.gov/pubmed/22543065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0b013e318254273e
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