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p53 Basic C Terminus Regulates p53 Functions through DNA Binding Modulation of Subset of Target Genes

The p53 gene encodes a transcription factor that is composed of several functional domains: the N-terminal transactivation domain, the central sequence-specific DNA binding domain, the tetramerization domain, and the highly basic C-terminal regulatory domain (CTD). The p53 CTD is a nonspecific DNA b...

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Detalhes bibliográficos
Main Authors: Hamard, Pierre-Jacques, Lukin, Dana J., Manfredi, James J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381199/
https://ncbi.nlm.nih.gov/pubmed/22514277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.331298
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