Načítá se...

Triazolothienopyrimidine Inhibitors of Urea Transporter UT-B Reduce Urine Concentration

Urea transport (UT) proteins facilitate the concentration of urine by the kidney, suggesting that inhibition of these proteins could have therapeutic use as a diuretic strategy. We screened 100,000 compounds for UT-B inhibition using an optical assay based on the hypotonic lysis of acetamide-loaded...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Yao, Chenjuan, Anderson, Marc O., Zhang, Jicheng, Yang, Baoxue, Phuan, Puay-Wah, Verkman, A.S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380644/
https://ncbi.nlm.nih.gov/pubmed/22491419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011070751
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!