Heat shock enhances CMV-IE promoter-driven metabotropic glutamate receptor expression and toxicity in transfected cells

In CHO-K1 cells, heat shock strongly activated reporter-gene expression driven by the cytomegalovirus immediate-early (CMV-IE) promoter from adenoviral and plasmid vectors. Heat shock treatment (2 hrs at 42.5°C) significantly enhanced the promoter DNA-binding activity in nuclear extracts. In CHO cel...

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Main Authors: Pshenichkin, Sergey, Surin, Alexander, Surina, Elena, Klauzińska, Małgorzata, Grajkowska, Ewa, Luchenko, Victoria, Dolińska, Monika, Wroblewska, Barbara, Wroblewski, Jarda T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380641/
https://ncbi.nlm.nih.gov/pubmed/21241715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2011.01.010
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