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Translating basic mechanisms of IgG effector activity into next generation cancer therapies

Monoclonal antibodies of the immunoglobulin G (IgG) isotype have become a well-established therapeutic tool for the targeting of malignant cells in tumor patients. Despite tremendous success in the treatment of lymphoma and breast cancer, it has also become clear that we may not be able to further i...

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Autori principali: Nimmerjahn, Falk, Ravetch, Jeffrey V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Academy of Cancer Immunology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380343/
https://ncbi.nlm.nih.gov/pubmed/22896758
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