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Translating basic mechanisms of IgG effector activity into next generation cancer therapies

Monoclonal antibodies of the immunoglobulin G (IgG) isotype have become a well-established therapeutic tool for the targeting of malignant cells in tumor patients. Despite tremendous success in the treatment of lymphoma and breast cancer, it has also become clear that we may not be able to further i...

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Bibliographic Details
Main Authors: Nimmerjahn, Falk, Ravetch, Jeffrey V.
Format: Artigo
Language:Inglês
Published: Academy of Cancer Immunology 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380343/
https://ncbi.nlm.nih.gov/pubmed/22896758
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