Hdac Activity is Required for Bdnf to Increase Quantal Neurotransmitter Release and Dendritic Spine Density in CA1 Pyramidal Neurons

Molecular mechanisms involved in the strengthening and formation of synapses include the activation and repression of specific genes or subsets of genes by epigenetic modifications that do not alter the genetic code itself. Chromatin modifications mediated by histone acetylation have been shown to b...

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Bibliographic Details
Main Authors: Calfa, Gaston, Chapleau, Christopher A., Campbell, Susan, Inoue, Takafumi, Morse, Sarah J., Lubin, Farah D., Pozzo-Miller, Lucas
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380176/
https://ncbi.nlm.nih.gov/pubmed/22161912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hipo.20990
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