Hippocampal CA1 Pyramidal Neurons of Mecp2 Mutant Mice Show a Dendritic Spine Phenotype Only in the Presymptomatic Stage

Alterations in dendritic spines have been documented in numerous neurodevelopmental disorders, including Rett Syndrome (RTT). RTT, an X chromosome-linked disorder associated with mutations in MECP2, is the leading cause of intellectual disabilities in women. Neurons in Mecp2-deficient mice show lowe...

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Bibliografiska uppgifter
Huvudupphovsmän: Chapleau, Christopher A., Boggio, Elena Maria, Calfa, Gaston, Percy, Alan K., Giustetto, Maurizio, Pozzo-Miller, Lucas
Materialtyp: Artigo
Språk:Inglês
Publicerad: Hindawi Publishing Corporation 2012
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418521/
https://ncbi.nlm.nih.gov/pubmed/22919518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/976164
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