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ERK1/2 Activation Is Necessary for BDNF to Increase Dendritic Spine Density in Hippocampal CA1 Pyramidal Neurons

Brain-derived neurotrophic factor (BDNF) is a potent modulator of synaptic transmission and plasticity in the CNS, acting both pre- and postsynaptically. We demonstrated recently that BDNF/TrkB signaling increases dendritic spine density in hippocampal CA1 pyramidal neurons. Here, we tested whether...

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Detalhes bibliográficos
Main Authors: Alonso, Mariana, Medina, Jorge H., Pozzo-Miller, Lucas
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC379687/
https://ncbi.nlm.nih.gov/pubmed/15054132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.67804
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