Glial Tumor Necrosis Factor Alpha (TNFα) Generates Metaplastic Inhibition of Spinal Learning

Injury-induced overexpression of tumor necrosis factor alpha (TNFα) in the spinal cord can induce chronic neuroinflammation and excitotoxicity that ultimately undermines functional recovery. Here we investigate how TNFα might also act to upset spinal function by modulating spinal plasticity. Using a...

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Autors principals: Huie, J. Russell, Baumbauer, Kyle M., Lee, Kuan H., Bresnahan, Jacqueline C., Beattie, Michael S., Ferguson, Adam R., Grau, James W.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3379985/
https://ncbi.nlm.nih.gov/pubmed/22745823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039751
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