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Glial Tumor Necrosis Factor Alpha (TNFα) Generates Metaplastic Inhibition of Spinal Learning

Injury-induced overexpression of tumor necrosis factor alpha (TNFα) in the spinal cord can induce chronic neuroinflammation and excitotoxicity that ultimately undermines functional recovery. Here we investigate how TNFα might also act to upset spinal function by modulating spinal plasticity. Using a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Huie, J. Russell, Baumbauer, Kyle M., Lee, Kuan H., Bresnahan, Jacqueline C., Beattie, Michael S., Ferguson, Adam R., Grau, James W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3379985/
https://ncbi.nlm.nih.gov/pubmed/22745823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039751
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