Glial Tumor Necrosis Factor Alpha (TNFα) Generates Metaplastic Inhibition of Spinal Learning

Injury-induced overexpression of tumor necrosis factor alpha (TNFα) in the spinal cord can induce chronic neuroinflammation and excitotoxicity that ultimately undermines functional recovery. Here we investigate how TNFα might also act to upset spinal function by modulating spinal plasticity. Using a...

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Detalhes bibliográficos
Main Authors: Huie, J. Russell, Baumbauer, Kyle M., Lee, Kuan H., Bresnahan, Jacqueline C., Beattie, Michael S., Ferguson, Adam R., Grau, James W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3379985/
https://ncbi.nlm.nih.gov/pubmed/22745823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039751
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