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Anesthetic Isoflurane Increases Phosphorylated Tau Levels Mediated by Caspase Activation and Aβ Generation

Anesthetic isoflurane has been shown to promote Alzheimer’s disease (AD) neuropathogenesis by inducing caspase activation and accumulation of β-amyloid (Aβ). Phosphorylation of tau protein is another important feature of AD neuropathogenesis. However, the effects of isoflurane on phosphorylated tau...

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מידע ביבליוגרפי
Main Authors: Dong, Yuanlin, Wu, Xu, Xu, Zhipeng, Zhang, Yiying, Xie, Zhongcong
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3379981/
https://ncbi.nlm.nih.gov/pubmed/22745746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039386
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