Carregant...

Structure–Activity Relationship for Thiirane-Based Gelatinase Inhibitors

[Image: see text] An extensive structure–activity relationship study with the template of 2-(4-phenoxyphenylsulfonylmethyl)thiirane (1), a potent and highly selective inhibitor for human gelatinases, is reported herein. Syntheses of 65 new analogues, each in multistep processes, allowed for explorat...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Lee, Mijoon, Ikejiri, Masahiro, Klimpel, Dennis, Toth, Marta, Espahbodi, Mana, Hesek, Dusan, Forbes, Christopher, Kumarasiri, Malika, Noll, Bruce C., Chang, Mayland, Mobashery, Shahriar
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2012
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3379896/
https://ncbi.nlm.nih.gov/pubmed/22737278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300050b
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!