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Pharmacological Validation of Trypanosoma brucei Phosphodiesterases as Novel Drug Targets
The development of drugs for neglected infectious diseases often uses parasite-specific enzymes as targets. We here demonstrate that parasite enzymes with highly conserved human homologs may represent a promising reservoir of new potential drug targets. The cyclic nucleotide-specific phosphodiestera...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3379837/ https://ncbi.nlm.nih.gov/pubmed/22291195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir857 |
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