The cAMP-specific phosphodiesterase TbPDE2C is an essential enzyme in bloodstream form Trypanosoma brucei

door Zoraghi, Roya, Seebeck, Thomas
Gepubliceerd in 2002

Polyoma Viral DNA Replicated as a Nucleoprotein Complex in Close Association with the Host Cell Chromatin

door Seebeck, Thomas, Weil, Roger
Gepubliceerd in 1974

Gene Conversion Transfers the GAF-A Domain of Phosphodiesterase TbrPDEB1 to One Allele of TbrPDEB2 of Trypanosoma brucei

door Kunz, Stefan, Luginbuehl, Edith, Seebeck, Thomas
Gepubliceerd in 2009

Phosphodiesterase inhibitors as a new generation of antiprotozoan drugs: exploiting the benefit of enzymes that are highly conserved between host and parasite

door Seebeck, Thomas, Sterk, Geert Jan, Ke, Hengming
Gepubliceerd in 2011

Cyclic nucleotide specific phosphodiesterases of Leishmania major

door Johner, Andrea, Kunz, Stefan, Linder, Markus, Shakur, Yasmin, Seebeck, Thomas
Gepubliceerd in 2006

The exopolyphosphatase TbrPPX1 of Trypanosoma brucei

door Luginbuehl, Edith, Kunz, Stefan, Wentzinger, Laurent, Freimoser, Florian, Seebeck, Thomas
Gepubliceerd in 2011

Crystal structure of the Leishmania major phosphodiesterase LmjPDEB1 and insight into the design of the parasite selective inhibitors

door Wang, Huanchen, Yan, Zier, Geng, Jie, Kunz, Stefan, Seebeck, Thomas, Ke, Hengming
Gepubliceerd in 2007

The N Terminus of Phosphodiesterase TbrPDEB1 of Trypanosoma brucei Contains the Signal for Integration into the Flagellar Skeleton

door Luginbuehl, Edith, Ryter, Damaris, Schranz-Zumkehr, Judith, Oberholzer, Michael, Kunz, Stefan, Seebeck, Thomas
Gepubliceerd in 2010

Polyamine-mediated phosphorylation of a nucleolar protein from Physarum polycephalum that stimulates rRNA synthesis

door Kuehn, Glenn D., Affolter, Hans-Urs, Atmar, Valerie J., Seebeck, Thomas, Gubler, Ueli, Braun, Richard
Gepubliceerd in 1979

Biological and Structural Characterization of Trypanosoma cruzi Phosphodiesterase C and Implications for Design of Parasite Selective Inhibitors

door Wang, Huanchen, Kunz, Stefan, Chen, Gong, Seebeck, Thomas, Wan, Yiqian, Robinson, Howard, Martinelli, Sibylla, Ke, Hengming
Gepubliceerd in 2012

Pharmacological Validation of Trypanosoma brucei Phosphodiesterases as Novel Drug Targets

door de Koning, Harry P., Gould, Matthew K., Sterk, Geert Jan, Tenor, Hermann, Kunz, Stefan, Luginbuehl, Edith, Seebeck, Thomas
Gepubliceerd in 2012

Discovery of novel Trypanosoma brucei phosphodiesterase B1 inhibitors by virtual screening against the unliganded TbrPDEB1 crystal structure

door Jansen, Chimed, Wang, Huanchen, Kooistra, Albert J., de Graaf, Chris, Orrling, Kristina, Tenor, Hermann, Seebeck, Thomas, Bailey, David, de Esch, Iwan J.P., Ke, Hengming, Leurs, Rob
Gepubliceerd in 2013

A Venom-derived Neurotoxin, CsTx-1, from the Spider Cupiennius salei Exhibits Cytolytic Activities

door Kuhn-Nentwig, Lucia, Fedorova, Irina M., Lüscher, Benjamin P., Kopp, Lukas S., Trachsel, Christian, Schaller, Johann, Vu, Xuan Lan, Seebeck, Thomas, Streitberger, Kathrin, Nentwig, Wolfgang, Sigel, Erwin, Magazanik, Lev G.
Gepubliceerd in 2012

Mechanisms of Arsenical and Diamidine Uptake and Resistance in Trypanosoma brucei

door Matovu, Enock, Stewart, Mhairi L., Geiser, Federico, Brun, Reto, Mäser, Pascal, Wallace, Lynsey J. M., Burchmore, Richard J., Enyaru, John C. K., Barrett, Michael P., Kaminsky, Ronald, Seebeck, Thomas, de Koning, Harry P.
Gepubliceerd in 2003