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Current clinical development of PI3K pathway inhibitors in glioblastoma
Glioblastoma (GBM) is the most common and lethal primary malignant tumor of the central nervous system, and effective therapeutic options are lacking. The phosphatidylinositol 3-kinase (PI3K) pathway is frequently dysregulated in many human cancers, including GBM. Agents inhibiting PI3K and its effe...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3379803/ https://ncbi.nlm.nih.gov/pubmed/22619466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nos117 |
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