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DECIPHERING INTRINSIC AND ADAPTIVE RESISTANCE TO PI3K PATHWAY INHIBITORS IN GLIOMA

BACKGROUND: Glioblastoma represents a compelling disease for signal transduction targeted therapy. Despite the evidence defining the PI3K network as a high quality target, regulatory feedback loops as well as cross talk with other networks make targeting the PI3K network a challenging task. Complete...

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Hlavní autoři: Yung, W.K. Alfred, Koul, Dimpy, Wu, Shaofang, Fu, Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144604/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou208.56
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