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DECIPHERING INTRINSIC AND ADAPTIVE RESISTANCE TO PI3K PATHWAY INHIBITORS IN GLIOMA
BACKGROUND: Glioblastoma represents a compelling disease for signal transduction targeted therapy. Despite the evidence defining the PI3K network as a high quality target, regulatory feedback loops as well as cross talk with other networks make targeting the PI3K network a challenging task. Complete...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4144604/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou208.56 |
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