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Inhibition of Glucose-Stimulated Insulin Secretion by KCNJ15, a Newly Identified Susceptibility Gene for Type 2 Diabetes

Potassium inwardly rectifying channel, subfamily J, member 15 (KCNJ15) is a type 2 diabetes–associated risk gene, and Kcnj15 overexpression suppresses insulin secretion in rat insulinoma (INS1) cells. The aim of the current study was to characterize the role of Kcnj15 by knockdown of this gene in vi...

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Bibliografiske detaljer
Main Authors: Okamoto, Koji, Iwasaki, Naoko, Doi, Kent, Noiri, Eisei, Iwamoto, Yasuhiko, Uchigata, Yasuko, Fujita, Toshiro, Tokunaga, Katsushi
Format: Artigo
Sprog:Inglês
Udgivet: American Diabetes Association 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3379671/
https://ncbi.nlm.nih.gov/pubmed/22566534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1201
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