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Inhibition of Glucose-Stimulated Insulin Secretion by KCNJ15, a Newly Identified Susceptibility Gene for Type 2 Diabetes

Potassium inwardly rectifying channel, subfamily J, member 15 (KCNJ15) is a type 2 diabetes–associated risk gene, and Kcnj15 overexpression suppresses insulin secretion in rat insulinoma (INS1) cells. The aim of the current study was to characterize the role of Kcnj15 by knockdown of this gene in vi...

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Main Authors: Okamoto, Koji, Iwasaki, Naoko, Doi, Kent, Noiri, Eisei, Iwamoto, Yasuhiko, Uchigata, Yasuko, Fujita, Toshiro, Tokunaga, Katsushi
格式: Artigo
語言:Inglês
出版: American Diabetes Association 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3379671/
https://ncbi.nlm.nih.gov/pubmed/22566534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1201
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