Inhibition of Glucose-Stimulated Insulin Secretion by KCNJ15, a Newly Identified Susceptibility Gene for Type 2 Diabetes

Potassium inwardly rectifying channel, subfamily J, member 15 (KCNJ15) is a type 2 diabetes–associated risk gene, and Kcnj15 overexpression suppresses insulin secretion in rat insulinoma (INS1) cells. The aim of the current study was to characterize the role of Kcnj15 by knockdown of this gene in vi...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Okamoto, Koji, Iwasaki, Naoko, Doi, Kent, Noiri, Eisei, Iwamoto, Yasuhiko, Uchigata, Yasuko, Fujita, Toshiro, Tokunaga, Katsushi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Diabetes Association 2012
Gaiak:
Islet Studies
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3379671/
https://ncbi.nlm.nih.gov/pubmed/22566534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1201
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