Inhibition of Glucose-Stimulated Insulin Secretion by KCNJ15, a Newly Identified Susceptibility Gene for Type 2 Diabetes

Potassium inwardly rectifying channel, subfamily J, member 15 (KCNJ15) is a type 2 diabetes–associated risk gene, and Kcnj15 overexpression suppresses insulin secretion in rat insulinoma (INS1) cells. The aim of the current study was to characterize the role of Kcnj15 by knockdown of this gene in vi...

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Detaylı Bibliyografya
Asıl Yazarlar: Okamoto, Koji, Iwasaki, Naoko, Doi, Kent, Noiri, Eisei, Iwamoto, Yasuhiko, Uchigata, Yasuko, Fujita, Toshiro, Tokunaga, Katsushi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Diabetes Association 2012
Konular:
Islet Studies
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3379671/
https://ncbi.nlm.nih.gov/pubmed/22566534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1201
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