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siRNA delivery targeting to the lung via agglutination-induced accumulation and clearance of cationic tetraamino fullerene

The efficient treatment of lung diseases requires lung-selective delivery of agents to the lung. However, lung-selective delivery is difficult because the accumulation of micrometer-sized carriers in the lung often induces inflammation and embolization-related toxicity. Here we demonstrate a lung-se...

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Bibliografiske detaljer
Main Authors: MINAMI, Kosuke, OKAMOTO, Koji, DOI, Kent, HARANO, Koji, NOIRI, Eisei, NAKAMURA, Eiichi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017229/
https://ncbi.nlm.nih.gov/pubmed/24814863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04916
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