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Functional and structural characterization of the mammalian TREX-2 complex that links transcription with nuclear messenger RNA export

Export of messenger RNA (mRNA) from the nucleus to the cytoplasm is a critical step in the gene expression pathway of eukaryotic cells. Here, we report the functional and structural characterization of the mammalian TREX-2 complex and show how it links transcription/processing with nuclear mRNA expo...

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Détails bibliographiques
Auteurs principaux: Jani, Divyang, Lutz, Sheila, Hurt, Ed, Laskey, Ronald A., Stewart, Murray, Wickramasinghe, Vihandha O.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378895/
https://ncbi.nlm.nih.gov/pubmed/22307388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks059
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