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Structural basis for binding the TREX2 complex to nuclear pores, GAL1 localisation and mRNA export
The conserved Sac3:Thp1:Sem1:Sus1:Cdc31 (TREX2) complex binds to nuclear pore complexes (NPCs) and, in addition to integrating mRNA nuclear export with preceding steps in the gene expression pathway, facilitates re-positioning of highly regulated actively transcribing genes (such as GAL1) to NPCs. A...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4041426/ https://ncbi.nlm.nih.gov/pubmed/24705649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku252 |
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