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Analysis of MRE11's function in the 5′→3′ processing of DNA double-strand breaks
The resection of DNA double-strand breaks (DSBs) into 3′ single-strand tails is the initiating step of homology-dependent repair pathways. A key player in this process is the MRE11-RAD50-NBS1 complex, but its contribution to and mechanistic role in resection are not well understood. In this study, w...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3378884/ https://ncbi.nlm.nih.gov/pubmed/22319209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks044 |
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