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Identification of the Xenopus DNA2 protein as a major nuclease for the 5′→3′ strand-specific processing of DNA ends

The first step of homology-dependent DNA double-strand break (DSB) repair is the 5′ strand-specific processing of DNA ends to generate 3′ single-strand tails. Despite extensive effort, the nuclease(s) that is directly responsible for the resection of 5′ strands in eukaryotic cells remains elusive. U...

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Bibliografski detalji
Glavni autori: Liao, Shuren, Toczylowski, Thomas, Yan, Hong
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577336/
https://ncbi.nlm.nih.gov/pubmed/18820296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn616
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