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Fibrin(ogen)-Independent Role of Plasminogen Activators in Acetaminophen-Induced Liver Injury
Hepatic fibrin(ogen) has been noted to occur after acetaminophen (APAP)-induced liver injury in mice. Deficiency in plasminogen activator inhibitor-1 (PAI-1), an endogenous inhibitor of fibrinolysis, increases APAP-induced liver injury in mice. However, the roles of fibrinogen and fibrinolysis in AP...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Investigative Pathology
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3378852/ https://ncbi.nlm.nih.gov/pubmed/22507835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.02.011 |
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