Activation of TLR4 is necessary for trauma hemorrhagic shock-induced gut injury and PMN priming

Interactions of Toll-like receptors (TLR) with non-microbial factors plays a major role in the pathogenesis of early trauma-hemorrhagic shock (T/HS)-induced organ injury and inflammation. Thus, we tested the hypothesis that TLR4 mutant (TLR4(mut)) mice would be more resistant to T/HS-induced gut inj...

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Autori principali: Reino, Diego C., Palange, David, Feketeova, Elenora, Bonitz, Robert P., Xu, Da Zhong, Lu, Qi, Sheth, Sharvil U., Peña, Geber, Ulloa, Luis, De Maio, Antonio, Feinman, Rena, Deitch, Edwin A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378823/
https://ncbi.nlm.nih.gov/pubmed/22575992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e318257123a
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