Trauma Hemorrhagic Shock-Induced Lung Injury Involves a Gut-Lymph-Induced TLR4 Pathway in Mice

BACKGROUND: Injurious non-microbial factors released from the stressed gut during shocked states contribute to the development of acute lung injury (ALI) and multiple organ dysfunction syndrome (MODS). Since Toll-like receptors (TLR) act as sensors of tissue injury as well as microbial invasion and...

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Auteurs principaux: Reino, Diego C., Pisarenko, Vadim, Palange, David, Doucet, Danielle, Bonitz, Robert P., Lu, Qi, Colorado, Iriana, Sheth, Sharvil U., Chandler, Benjamin, Kannan, Kolenkode B., Ramanathan, Madhuri, Xu, Da Zhong, Deitch, Edwin A., Feinman, Rena
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
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Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150139/
https://ncbi.nlm.nih.gov/pubmed/21829592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014829
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