Trauma Hemorrhagic Shock-Induced Lung Injury Involves a Gut-Lymph-Induced TLR4 Pathway in Mice

BACKGROUND: Injurious non-microbial factors released from the stressed gut during shocked states contribute to the development of acute lung injury (ALI) and multiple organ dysfunction syndrome (MODS). Since Toll-like receptors (TLR) act as sensors of tissue injury as well as microbial invasion and...

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Hauptverfasser: Reino, Diego C., Pisarenko, Vadim, Palange, David, Doucet, Danielle, Bonitz, Robert P., Lu, Qi, Colorado, Iriana, Sheth, Sharvil U., Chandler, Benjamin, Kannan, Kolenkode B., Ramanathan, Madhuri, Xu, Da Zhong, Deitch, Edwin A., Feinman, Rena
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150139/
https://ncbi.nlm.nih.gov/pubmed/21829592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014829
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