Trauma Hemorrhagic Shock-Induced Lung Injury Involves a Gut-Lymph-Induced TLR4 Pathway in Mice

BACKGROUND: Injurious non-microbial factors released from the stressed gut during shocked states contribute to the development of acute lung injury (ALI) and multiple organ dysfunction syndrome (MODS). Since Toll-like receptors (TLR) act as sensors of tissue injury as well as microbial invasion and...

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Autors principals: Reino, Diego C., Pisarenko, Vadim, Palange, David, Doucet, Danielle, Bonitz, Robert P., Lu, Qi, Colorado, Iriana, Sheth, Sharvil U., Chandler, Benjamin, Kannan, Kolenkode B., Ramanathan, Madhuri, Xu, Da Zhong, Deitch, Edwin A., Feinman, Rena
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150139/
https://ncbi.nlm.nih.gov/pubmed/21829592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014829
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