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In vivo delivery of cell-permeable antisense hypoxia-inducible factor 1α oligonucleotide to adipose tissue reduces adiposity in obese mice

Ongoing research has gradually recognized and understood the importance of adipose tissue (AT) angiogenesis as a key modulating factor of adipogenesis in the development of obesity. Previously, we carried out the first in vitro demonstration of the down-regulation of hypoxic angiogenesis during adip...

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Hlavní autoři: Park, Yoon Shin, David, Allan E., Huang, Yongzhuo, Park, Jun-Beom, He, Huining, Byun, Youngro, Yang, Victor C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378795/
https://ncbi.nlm.nih.gov/pubmed/22546680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2012.04.026
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