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The TP53 tumor suppressor and autophagy in malignant lymphoma

The TP53 (p53) protein is a well-known tumor suppressor that plays a crucial role in maintaining genome stability under various cellular stresses. Loss of TP53 causes lymphomagenesis in mouse models and/or promotes tumor progression. However, the prognostic significance of TP53 has been inconsistent...

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Bibliographic Details
Main Authors: Xu-Monette, Zijun Y., Young, Ken H.
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378422/
https://ncbi.nlm.nih.gov/pubmed/22498492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.19703
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