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Dysfunction of the TP53 tumor suppressor gene in lymphoid malignancies
Mutations of the TP53 gene and dysregulation of the TP53 pathway are important in the pathogenesis of many human cancers, including lymphomas. Tumor suppression by p53 occurs via both transcription-dependent activities in the nucleus by which p53 regulates transcription of genes involved in cell cyc...
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Asıl Yazarlar: | , , , , , , , , |
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Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
American Society of Hematology
2012
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3335376/ https://ncbi.nlm.nih.gov/pubmed/22275381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-11-366062 |
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