Dysfunction of the TP53 tumor suppressor gene in lymphoid malignancies

Mutations of the TP53 gene and dysregulation of the TP53 pathway are important in the pathogenesis of many human cancers, including lymphomas. Tumor suppression by p53 occurs via both transcription-dependent activities in the nucleus by which p53 regulates transcription of genes involved in cell cyc...

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Detaylı Bibliyografya
Asıl Yazarlar: Xu-Monette, Zijun Y., Medeiros, L. Jeffrey, Li, Yong, Orlowski, Robert Z., Andreeff, Michael, Bueso-Ramos, Carlos E., Greiner, Timothy C., McDonnell, Timothy J., Young, Ken H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2012
Konular:
Review Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335376/
https://ncbi.nlm.nih.gov/pubmed/22275381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-11-366062
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