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Modulation of neuronal sodium channels by the sea anemone peptide BDS-I

Blood-depressing substance I (BDS-I), a 43 amino-acid peptide from sea anemone venom, is used as a specific inhibitor of Kv3-family potassium channels. We found that BDS-I acts with even higher potency to modulate specific types of voltage-dependent sodium channels. In rat dorsal root ganglion (DRG)...

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Hlavní autoři: Liu, Pin, Jo, Sooyeon, Bean, Bruce P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378363/
https://ncbi.nlm.nih.gov/pubmed/22442564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00785.2011
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