Modulation of Kv3 Subfamily Potassium Currents by the Sea Anemone Toxin BDS: Significance for CNS and Biophysical Studies

Kv3 potassium channels, with their ultra-rapid gating and high activation threshold, are essential for high-frequency firing in many CNS neurons. Significantly, the Kv3.4 subunit has been implicated in the major CNS disorders Parkinson's and Alzheimer's diseases, and it is claimed that sel...

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Autors principals: Yeung, Shuk Yin M., Thompson, Dawn, Wang, Zhuren, Fedida, David, Robertson, Brian
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2005
Matèries:
Cellular/Molecular
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1314979/
https://ncbi.nlm.nih.gov/pubmed/16177043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2119-05.2005
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